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Huntington’s Disease

Huntington's disease or Huntington’s chorea (HD) is a rare inherited disorder characterized by abnormal body movements called chorea, and a reduction of various mental abilities. It takes its name from the Ohio physician George Huntington who described it precisely in 1872.

The symptoms of Huntington’s disease occur gradually over time - there is no sudden loss of abilities and it is hard to determine when symptoms initially occur. One-half to three-fourths of the patients present abnormal movement or rigidity. The remainder of the patients present mental status changes, such as irritability, moodiness, or antisocial behavior. Most of the patients eventually exhibit chorea, which is jerky, random, uncontrollable, rapid movements. Typically, the abnormal movements begin at the extremities and then later progress.

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Last modified: 2006-10-18

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